IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes，mast cells，erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Whereas murine IL-9 can function on human cells，human IL-9 is inactive on mouse cells.
應用類型
1） WB: Use 0.1-0.2 ug/ml. The detection limit for recombinant human IL-9 is 1.5-3.0 ng/lane， under either reducing or non-reducing conditions. 2） ELISA: Use 0.5 - 2.0 ug/ml （100 ul/well antibody solution） 3） Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Human IL-9 （5.0 ng/ml）， a concentration of 1.0-2.0 ug/ml of this antibody is required.
