Furin is a ubiquitous protein located within the trans-Golgi network. It is found in many tissues and cell lines including MDCK,HeLa,HepG2 and NIH-3T3. Furin is a proprotein convertase that is responsible for the proteolytic maturation of many precursor proteins that are secreted from the constitutive secretory pathway
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~95-110 kDa Furin/PACE. A splice variant (~60 kDa) can also be detected.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 779 of mouse Furin/PACE
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠、牛、綿羊種屬來源的Furin/PACE蛋白發生免疫反應.
保存建議
提供的Furin/PACE抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Furin/PACE抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.