Lysine-specific demethylase 1(LSD1) is also known as AOF2, is a nuclear amine oxidase. LSD1 contain a Swirm domain, a FAD-binding motif and an amine oxidase domain that can act as a histone demethylase as well as transcription cofactor. LSD1 activity is inhibited by the amine oxidase inhibitors pargyline, deprenyl, clorgyline and tranylcypromine
應用類型
Western blotting (2-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 127of rat LSD1/AOF2
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的LSD1/AOF2蛋白發生免疫反應
保存建議
提供的100 ug LSD1/AOF2抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該LSD1/AOF2抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.