- 中文名稱
Prostaglandin D2-d4 (1 mg)
- 英文名字
- PGD2-d4, Prostaglandin D2-d4, 9
- 供應商
- Cayman
- 產品貨號
- 312010-1
- 產品報價
- ￥27832/1 mg
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3 , 4, and 4 positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as .beta.-trace.2,3 In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 uM.
- 產品描述
- An internal standard for the quantification of PGD2 by GC- or LC-MS
- 產品形式
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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