N-（R）-α-羥基四cosanoyl-植物鞘氨醇-N-(R)-alpha-Hydroxytetracosanoyl-phytosphingosine代理/參數/廠家-標準品（生化）-艾美捷科技有限公司

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背景資料: Phytosphingosine is a long-chain sphingoid base having important cellular functions such as signaling, skin barrier function, cytoskeletal structure, celluar cycle, and heat stress response. It is found largely in mammals, plants, and yeast. Phytosphingosine has seen much use in cosmetics due to its effects on the skin such as reducing inflammation by inhibiting the expression of the allergic cytokines IL-4 and TNF-α and the activation of the transcription factors NF-jB and c-jun in histamine-stimulated skin tissues.1 Phytosphingosine can lead to apoptosis via two distinct pathways and has been investigated as a possible cancer therapeutic treatment.2 Phytoceramides are distributed at the microvillous membrane of the epithelial cells of the small intestine. Crypt cells and the adjacent epithelial cells produce phytosphingoglycolipids in much greater quantities than more differentiated epithelial cells.3 The kidney and skin also contain phytosphingoglycolipids although in much lower concentrations than in the small intestine. Skin cells contain significant amounts of long chain ceramides, such as alpha-hydroxyphytoceramides, that are vital for maintaining skin barrier functions.4

產品描述: N-(R)-alpha-Hydroxy-C24:0-phytoceramide|N-(R)-Cerebronoyl-phytoceramide

其他: Matreya LLC是一家脂質生化公司，致力于開發和制造高質量的脂質和生物化學品。Matreya在化學合成以及天然產物提取和純化方面經驗豐富，生產出的產品具有最佳純度。 Matreya產品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構體（生育酚和生育三烯酚）。專長是生產高純度鞘氨醇、神經酰胺、硫酸酯、神經節苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質產品最全的供應商之一。產品涉及生物化學、制藥、微生物學、食品和農業等研究領域。