中文名稱

Haptoglobin, Rat

英文名字

Haptoglobin, Rat

供應商

USBiological

產品貨號

208938

產品報價

￥1/25ug

產品說明書

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購買方式

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產品新聞

背景資料

USBiological品牌是全球有名的抗原抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區域總代理，是行業中少有的致力于服務客戶，幫助客戶，且擁有獨立的專業銷售團隊、技術支持團隊、市場營銷團隊、進出口報關團隊的高科技生物企業。可以為您提供及時的咨詢響應，專業的產品和解決方案支持，穩健快捷的交貨周期，優質放心的售后服務。我們致力于為您提供有價值的產品和服務，在意您的成功！

產品描述

Haptoglobin (also known as Haptoglobin, alpha polypeptide antibody, Haptoglobin, beta polypeptide antibody, HP antibody, Hp2 alpha antibody, HP2 ALPHA2 antibody,HPA1S antibody, HPT antibody, MGC111141 antibody as Hp) is a protein that in humans is encoded by the HP gene. In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticulo-endothelial system (mostly the spleen).This HP gene encodes a precursor that is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Haptoglobin is produced mostly by hepatocytes but also by other tissues: e.g., skin, lung, and kidney. In addition, the haptoglobin gene is expressed in mouse and human adipose tissue.Haptoglobin, in its simplest form, consists of two alpha- and two beta- chains, connected by disulfide bridges. Hp exists in two allelic forms in the human population, so-called Hp1 and Hp2, the latter one having arisen due to the partial duplication of Hp1 gene. Three phenotypes of Hp, therefore, are found in humans: Hp1-1, Hp2-1, and Hp2-2. Hp of different phenotypes have been shown to bind hemoglobin with different affinities, with Hp2-2 being the weakest binder. The amino acid sequence of Hp1-1 consists of 406aa, it has molecular weight of about 45kD.Source:Haptoglobin, from rat plasmaMolecular Weight:~40kD and 10kD (SDS-PAGE)Applications: Suitable for use in ELISA and Western Blot. Other applications not tested.Recommended Dilution:ELISA: 1:1000 Optimal dilutions to be determined by the researcher.Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

產品形式

該產品為凍干粉，緩沖液為：sterile PBS, pH 7.4。

保存建議

接收到Haptoglobin, Rat產品后，置于-20°C溫度下保存。

其他

Usbiological公司是美國著名的抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。Usbiological公司現已擁有超過50,19234種抗體、抗原和生化產品，為科研用戶提供了諸多超值選擇。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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