- 中文名稱
14,15-dehydro Leukotriene B4 (500 ug)
- 英文名字
- 14,15-dehydro LTB4, 14,15-dehydro Leukotriene B4, 5S,12R-dihydroxy-6Z,8E,1E-eicosatrien-14-ynoic acid
- 供應商
- Cayman
- 產品貨號
- 20150-500
- 產品報價
- ￥23968/500 ug
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 uM.
- 產品描述
- A LTB4 receptor antagonist that has a higher binding affinity for BLT1 (Ki = 27 nM) compared to BLT2 (Ki = 473 nM); inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 uM
- 產品形式
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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