- 中文名稱
20-ethyl Prostaglandin E2 (50 mg)
- 英文名字
- 2-ethyl PGE2, 20-ethyl Prostaglandin E2, 9-oxo-11.alpha.,15S-dihydroxy-2a,2b-dihomoprosta-5Z,13E-dien-1-oic acid
- 供應商
- Cayman
- 產品貨號
- 14940-50
- 產品報價
- ￥22540/50 mg
- 產品說明書
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- 購買方式
- 產品新聞
- 背景資料
- 20-ethyl Prostaglandin E2 -20-ethyl PGE2) is an analog of PGE2 in which the .omega.-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is clinically approved as a glaucoma medication. Unoprostone also contains lower side chain modifications -13,14-dihydro-15-keto) which severely limit its affinity for FP receptors, contributing to its lack of potency as a medication. 20-ethyl PGE2 retains the natural 15-S) allylic hydroxyl in the lower side chain, which may improve its potency relative to unoprostone. However, ligand binding assays of this analog with respect to EP or other prostanoid receptors have not been published. E-type prostaglandins have been widely reported to have inflammatory, cytoprotective, and a variety of other effects.
- 產品描述
- 20-ethyl PGE2 is an analog of PGE2 in which the .omega.-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is clinically approved as a glaucoma medication.{8147} Unoprostone also contains lower side chain modifications -13,14-dihydro-15-keto) which severely limit its affinity for FP receptors, contributing to its lack of potency as a medication. 20-ethyl PGE2 retains the natural 15-S) allylic hydroxyl in the lower side chain, which may improve its potency relative to unoprostone. However, ligand binding assays of this analog with respect to EP or other prostanoid receptors have not been published. E-type prostaglandins have been widely reported to have inflammatory,{5381} cytoprotective,{2216} and a variety of other effects.{1558}
- 產品形式
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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