中文名稱

D，L-赤型-二氫鞘氨醇（鞘氨醇激酶抑制劑）

英文名字

D,L-erythro-Dihydrosphingosine (Inhibitor of Sphingosine Kinase)

供應商

Matreya

產品貨號

1324-25

產品報價

￥詢價/25mg

產品說明書

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購買方式

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產品新聞

背景資料

This dihydrosphingosine standard is a mixture of D and L isomers and contains approximately 77% erythro and 23% threo isomers. It is an 18 carbon chain which is the most prevalent dihydrosphingosine chain length in most animals. However, some animals, such as Drosophila melanogaster, have the shorter C16 dihydrosphingosine base1 while C20 sphingoid bases are the most prevalent in some microorganisms and are usually the second most abundant sphingoid base in mammals. Dihydrosphingosine (Sphinganine) is the precursor of dihydroceramide which is then desaturated to form ceramide. It is a critical intermediate in the synthesis of many complex sphingoid bases and ceramide analogs. It has been found that sphinganine can induce cell death in a number of types of malignant cells and is being tested for its pharmacological properties.2 Inhibition of dihydroceramide synthesis by some fungal toxins that have a similar structure causes an increase in sphinganine and sphinganine-1-phosphate and a decrease in other sphingolipids leading to a number of diseases including oesophageal cancer.3 Sphinganine has been found to mediate fumonisin (a toxic sphinganine analog) induced hypotension.4 In yeast the amount of C20-dihydrosphingosine increases as a response to heat stress, along with other sphingolipids, indicating that it is involved in heat stress adaptation.

產品描述

D,L-erythro-Sphinganine, C18 chain

產品形式

該D，L-赤型-二氫鞘氨醇（鞘氨醇激酶抑制劑）產品為固體形式

保存建議

對于本產品，我們推薦使用-20℃藍冰低溫進行運輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說明請參考本品說明書。

其他

Matreya LLC是一家脂質生化公司，致力于開發和制造高質量的脂質和生物化學品。Matreya在化學合成以及天然產物提取和純化方面經驗豐富，生產出的產品具有最佳純度。 Matreya產品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構體（生育酚和生育三烯酚）。專長是生產高純度鞘氨醇、神經酰胺、硫酸酯、神經節苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質產品最全的供應商之一。產品涉及生物化學、制藥、微生物學、食品和農業等研究領域。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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