中文名稱

L-蘇糖基鞘氨醇磷酸膽堿

英文名字

L-threo-Sphingosylphosphorylcholine

供應商

Matreya

產品貨號

1319-5

產品報價

￥詢價/5mg

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868

產品新聞

背景資料

This product is the highly purified L-threo-sphingosylphosphorylcholine isomer which has distinct functionality from the natural D-erythro isomer. SPC is similar in structure to sphingosine-1-phosphate and lyso-phosphatidylcholine and has at least low-binding affinity to some of the same receptors such as the sphingosine-1-phosphate receptor. SPC is a bioactive lipid that acts as an intracellular and extracellular signalling molecule in numerous biological processes and activates various signaling cascades. Some of these signaling responses include vasoconstriction, vasodilation, angiogenesis, stress fiber formation, cytoskeletal rearrangements, proliferation, differentiation, migration, wound healing, and stimulation of DNA synthesis. SPC can also inhibit the growth of various cell types, mostly that of tumor cells causing much interest in its possible role as an anti-tumor therapy. SPC is a high-affinity ligand for the orphan receptor ovarian cancer G-protein-coupled receptor 1 (OGR1). The specific binding of SPC to OGR1 also activates p42/44 mitogen-activated protein kinases (MAP kinases) and inhibits cell proliferation.1 SPC acts as an inhibitor for calmodulin, a highly prevalent intracellular calcium sensor in eukaryotic cells.2 The extracellular effects of SPC appear to be stereospecific while intracellular effects are not. Derythro- SPC, but not L-threo-SPC, stereoselectively stimulate an increase in calcium concentration and cellular proliferation.3 Both the L-threo SPC isomer and the D-erythro SPC isomer can act as second messengers by releasing calcium from internal stores.

產品描述

L-threo-SPC

產品形式

該L-蘇糖基鞘氨醇磷酸膽堿產品為固體形式

保存建議

對于本產品，我們推薦使用-20℃藍冰低溫進行運輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說明請參考本品說明書。

其他

Matreya LLC是一家脂質生化公司，致力于開發和制造高質量的脂質和生物化學品。Matreya在化學合成以及天然產物提取和純化方面經驗豐富，生產出的產品具有最佳純度。 Matreya產品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構體（生育酚和生育三烯酚）。專長是生產高純度鞘氨醇、神經酰胺、硫酸酯、神經節苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質產品最全的供應商之一。產品涉及生物化學、制藥、微生物學、食品和農業等研究領域。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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