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中文名稱

11-deoxy-11-methylene-15-keto Prostaglandin D2 (5 mg)

英文名字
11-deoxy-11-methylene-15-keto PGD2, 11-deoxy-11-methylene-15-keto Prostaglandin D2, 9.alpha.-hydroxy-11-methylene-15-oxo-prosta-5Z,13E-dien-1-oic acid
供應商
Cayman
產品貨號
12415-5
產品報價
¥22540/5 mg
產品說明書
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背景資料
Prostaglandin D2 -PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor. However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2. This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2. 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2.
產品描述
PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor.{3128} However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2.{10058,10722} This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2.{9769} 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2.
產品形式
保存建議
-20
其他
Cayman Chemical
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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