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中文名稱

Anti-Rat Aminopeptidase P

英文名字
Anti-Rat Aminopeptidase P
供應商
ReliaTech
產品貨號
104-M01
產品報價
¥詢價/100ug
產品說明書
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背景資料
Aminopeptidase P (AP-P; X-Pro aminopeptidase) has the unique ability to leave the N-terminal amino acid residue from peptides having proline as the penultimate amino acid residue. Biologically active peptides comprise an important and diverse class of extracellular chemical messengers that mediate a wide range of intercellular interactions. Several bioactive peptides including hormones, neuropeptides, neurotransmitters escape non-specific protease degradation by having an Xaa-Pro motif at their amino termini. Due to its cyclic nature, proline confers resistance to such peptide bonds so that aminopeptidases with broad specificity cannot act upon such peptides. There are a limited number of peptidases that act on peptide bonds involving a proline residue, such as dipeptidyl peptidase II (DPPII) and dipeptidyl peptidase W (DPPIV), and prolidase (which cleaves the Xaa-Pro bond only in dipeptides), or endopeptidases such as prolyl endopeptidase (which cleaves on the carbonyl side of proline residues within a protein or peptide). However,of these enzymes have been reported to hydrolyze Xaa-Pro bonds located at the N-terminus of peptides and proteins. Therefore, role of AP-P is crucial in this respect. AP-P activity is ubiquitous and has been found in a wide range of organisms including bacteria, yeast and vertebrates. Mammalian AP-Ps exist in membrane-bound and cytosolic forms, which represent two distinct gene products. The cytosolic (soluble) form of aminopeptidase P is found in human leukocytes and rat brain.
應用類型
IHC
免疫原
該Anti-Rat Aminopeptidase P的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
Mouse
反應性
該Anti-Rat Aminopeptidase P的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Rat Aminopeptidase P的詳細信息查看ReliaTech提供的產品說明書。
其他
ReliaTech全稱為受體配體技術有限公司 (Receptor Ligand Technologies GmbH),1999年成立,總部位于德國不倫瑞克,是一家后基因組生物技術公司。ReliaTech主要專注于受體和配體的發現與研究。此外,ReliaTech也開發應用于血管與淋巴管生成研究的相關高品質試劑。目前ReliaTech提供近2800款產品,產品線主要包括重組蛋白(細胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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