Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.
應用類型
WB
免疫原
該Anti-Mouse Granzyme B的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Mouse Granzyme B的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Mouse Granzyme B的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Mouse Granzyme B的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
