- 中文名稱
Anti-Mouse Frizzled-7
- 英文名字
- Anti-Mouse Frizzled-7
- 供應商
- ReliaTech
- 產品貨號
- 103-M388
- 產品報價
- ￥詢價/100ug
- 產品說明書
- 點擊查看
- 購買方式
- 90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- The Wnt genes encode a large family of glycoproteins that are essential in development and tissue maintenance. Members of the Frizzled family of proteins serve as receptors for the Wnt signaling pathway. The predicted structure of Frizzled proteins is similar among all family members, containing a divergent N-terminal signal peptide, a highly conserved extracellular cysteine-rich domain (CRD), a variable length linker region, a seven-pass transmembrane region, and a variablelength C-terminal cytoplasmic domain. The CRD, which comprises the Wnt binding site, spans about 130 amino acid residues and contains ten invariant cysteine residues. Mouse Frizzled-7 contains 572 amino acid residues and shares 99% identity with the human orthologue in the CRD. Frizzled7 mRNA has been detected in relatively large amounts in adult skeletal muscle, plancenta and heart, and fetal kidney and lung. Several Frizzled-dependent signaling pathways exist. Their activation depends on the Wnt ligand and the cell context. Frizzled-7 can activate canonical Wnt/βCatenin signaling, as well as a noncanonical pathway involved in tissue morphogenesis.
- 應用類型
- WB
- 免疫原
- 該Anti-Mouse Frizzled-7的詳細信息查看ReliaTech提供的產品說明書。
- 來源宿主
- 該Anti-Mouse Frizzled-7的詳細信息查看ReliaTech提供的產品說明書。
- 反應性
- 該Anti-Mouse Frizzled-7的詳細信息查看ReliaTech提供的產品說明書。
- 保存建議
- 該Anti-Mouse Frizzled-7的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
- 其他
- ReliaTech全稱為受體配體技術有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，總部位于德國不倫瑞克，是一家后基因組生物技術公司。ReliaTech主要專注于受體和配體的發現與研究。此外，ReliaTech也開發應用于血管與淋巴管生成研究的相關高品質試劑。目前ReliaTech提供近2800款產品，產品線主要包括重組蛋白(細胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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