- 中文名稱
抗PCSK9多克隆抗體
- 英文名字
- PCSK9 Polyclonal Antibody
- 供應商
- Cayman
- 產品貨號
- 10240-500
- 產品報價
- ￥3556/500 μl
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- PCSK9 is a member of the subtilisin serine protease family with an important role in low-density lipoprotein -LDL) metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels. PCSK9 overexpression in wild-type mice doubles the plasma total cholesterol, possibly through acceleration of the degradation of the LDL receptor. PCSK9 mRNA is detected in various tissues such as liver, kidney, lung, spleen, jejunum, ileum, colon, and muscles with the highest expression in the liver. Human PCSK9 precursor is 692 amino acids in length with an estimated molecular weight of 74 kDa. This proprotein is self-cleaved to form a mature protein of 63 kDa in the Golgi.
- 應用類型
- WB and ICC
- 免疫原
- human recombinant PCSK9
- 來源宿主
- rabbit
- 反應性
- Human PCSK9+|Rat PCSK9+|Murine PCSK9+
- 保存建議
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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