Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self renewal via a STAT3 independent pathway. Recombinant human Nanog is a 35 kDa protein, which is synthesized as a 304 amino acid polypeptide lacking a signal sequence for secretion.
應用類型
ELISA, WB
免疫原
該Anti-Human Nanog的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
Rabbit
反應性
該Anti-Human Nanog的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human Nanog的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
