- 中文名稱
BM 567 (50 mg)
- 英文名字
- BM 567, 2-(cyclohexylamino)-5-nitro-N-[(pentylamino)carbonyl]-benzenesulfonamide
- 供應商
- Cayman
- 產品貨號
- 10155-50
- 產品報價
- ￥22540/50 mg
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Thromboxane A2 -TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large quantities by activated platelets. TXA2 has been implicated as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of TXA2 synthase and as an antagonist of the TP receptor, the G protein-coupled receptor mediating TXA2 activity in platelets and vascular smooth muscle. BM 567 antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. It inhibits platelet TX synthase with an IC50 value of 12 nM.
- 產品描述
- TXA2 is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large quantities by activated platelets. TXA2 has been implicated as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of TXA2 synthase and as an antagonist of the TP receptor, the GPCR mediating TXA2 activity in platelets and vascular smooth muscle. BM 567 antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. It inhibits platelet TX synthase with an IC50 value of 12 nM.{12979}
- 產品形式
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
