Osteoprotegerin (OPG)/osteoclastogenesis inhibitory factor (OCIF) is a member of the TNF receptor superfamily and is now referred to as TNFRSF11B. It is an osteoblast secreted decoy receptor that binds specifically to osteoprotegrin ligand (OPGL/TNFSF11) to inhibit osteoblast maturation. It is also a decoy receptor for TRAIL and inhibits TRAIL-induced apoptosis. Human and mouse OPG share approximately 84% and 94% amino acid sequence identity, respectively, with rat OPG. Natural OPG exists predominantly as disulfide-linked dimers.
應用類型
WB, N
免疫原
該Anti-Human TNFRSF11B的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human TNFRSF11B的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human TNFRSF11B的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human TNFRSF11B的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
