Pin1 is a peptidylprolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/TP). Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53,NFκB, cJun, cyclin D1, and βcatenin.
應用類型
WB
免疫原
該Anti-Human PIN的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human PIN的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human PIN的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human PIN的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
