NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
應用類型
WB
免疫原
該Anti-Human NKG2A的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human NKG2A的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human NKG2A的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human NKG2A的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
