Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1, ANG-2, and ANG-3 (mouse)/-4 (human). It is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2.
應用類型
WB, IHC
免疫原
該Anti-Human TIE-1的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human TIE-1的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human TIE-1的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human TIE-1的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
