The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.
應用類型
WB
免疫原
該Anti-Human Common beta chain的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human Common beta chain的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human Common beta chain的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human Common beta chain的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
