Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the β site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).
應用類型
WB
免疫原
該Anti-Human Cathepsin E的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human Cathepsin E的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human Cathepsin E的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human Cathepsin E的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
