The gene for the antigen encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
應用類型
WB, FC
免疫原
該Anti-Human ADAM-17的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human ADAM-17的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human ADAM-17的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human ADAM-17的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
