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中文名稱

Anti-Human FAS

英文名字
Anti-Human FAS
供應商
ReliaTech
產品貨號
101-M134
產品報價
¥詢價/100ug
產品說明書
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產品新聞
背景資料
Fas, also known as APO1, CD95, and TNFRSF6, was originally identified as a cellsurface protein which binds to monoclonal antibodies that were cytolytic for various human cell lines. In the new TNF Receptor superfamily nomenclature, Fas is referred to as TNFRSF6. Human Fas cDNA encodes a 325 amino acid (aa) residue type 1 membrane protein that belongs to the TNF and NGF receptor family. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas lacking the transmembrane domain, have also been identified. Fas is highly expressed in epithelial cells, hepatocytes, activated mature lymphocytes, virus-transformed lymphocytes, and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary. The ligand for Fas (FasL) has been identified and shown to be a member of the TNF family of type 2 membrane proteins. Fas-L is predominantly expressed by activated Tlymphocytes, NK cells, and in tissues with immuneprivileged sites. Soluble Fas-L can be produced by proteolysis of membrane-associated Fas.
應用類型
WB, IHC (P)
免疫原
該Anti-Human FAS的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
該Anti-Human FAS的詳細信息查看ReliaTech提供的產品說明書。
反應性
該Anti-Human FAS的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human FAS的詳細信息查看ReliaTech提供的產品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
其他
ReliaTech全稱為受體配體技術有限公司 (Receptor Ligand Technologies GmbH),1999年成立,總部位于德國不倫瑞克,是一家后基因組生物技術公司。ReliaTech主要專注于受體和配體的發現與研究。此外,ReliaTech也開發應用于血管與淋巴管生成研究的相關高品質試劑。目前ReliaTech提供近2800款產品,產品線主要包括重組蛋白(細胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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