- 中文名稱
14,15-Leukotriene E4 (500 ug)
- 英文名字
- Eoxin E4|EXE4|14,15-LTE4, 14,15-Leukotriene E4, 15S-hydroxy-14R-(S-cysteinyl)-5Z,8Z,1E,12E-eicosatetraenoic acid
- 供應商
- Cayman
- 產品貨號
- 10011362-500
- 產品報價
- ￥23968/500 ug
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Leukotrienes -LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase -5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. These metabolites are classified as eoxins because they are formed mostly by eosinophils. Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine.
- 產品描述
- A metabolite of 14,15-LTC4 and 14,15-LTD4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine
- 產品形式
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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