- 中文名稱
Harmine (5 g)
- 英文名字
- Harmine, 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
- 供應商
- Cayman
- 產品貨號
- 10010324-5
- 產品報價
- ￥3584/5 g
- 產品說明書
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- 購買方式
- 產品新聞
- 背景資料
- Peroxisome proliferator-activated receptor .gamma. -PPAR.gamma.) is a central regulator of adipocyte differentiation and is the principle target of the thiazolidinedione -TZD) class of antidiabetic drugs. Harmine is a .beta.-carboline alkaloid that was first isolated from seeds of Peganum harmala -Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPAR.gamma. expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner. Administration of harmine -30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression -TNF.alpha., IL-1.beta., iNOS) and macrophage accumulation in adipose tissue.
- 產品描述
- Harmine is a .beta.-carboline alkaloid that was first isolated from seeds of Peganum harmala -Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPAR.gamma. expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner.{14921} Administration of harmine -30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression -TNF.alpha., IL-1.beta., iNOS) and macrophage accumulation in adipose tissue.{14921}
- 產品形式
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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