- 中文名稱
Akt(人重組蛋白)WB即用型對照 (1 ea)
- 英文名字
- Akt -human recombinant) Western Ready Control (1 ea)
- 供應商
- Cayman
- 產品貨號
- 10010079-1
- 產品報價
- ¥714/1 ea

- 產品說明書
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- 背景資料
- Akt is a serine/threonine kinase that has been implicated in cell survival, cell proliferation, insulin signaling, and is often found to be over expressed in many kinds of human tumors. There are three isoforms of Akt -Akt1 Akt2, and Akt3) that differ in their cellular location and expression levels. Activated PI3K catalyzes the formation of PI-3,4)P2 and PI-3,4,5)P3. These phospholipids act as second messengers to recruit Akt to the plasma membrane through binding of the PH domain. Akt then becomes phosphorylated on threonine 308 and serine 473 to become a fully active kinase. Akt is down regulated by the serine/threonine protein phosphatases PP2A and .lambda.PP.
- 序列
- 來源宿主
- 溶解建議
- 保存建議
- -20
- 其他
- Cayman Chemical

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