- 中文名稱
血清視黃醇結合蛋白WB即用型對照 (1 ea)
- 英文名字
- Serum Retinol Binding Protein Western Ready Control (1 ea)
- 供應商
- Cayman
- 產品貨號
- 10009754-1
- 產品報價
- ￥714/1 ea
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Human serum retinol binding protein 4 -sRBP4) binds to one equivalent of vitamin A and is one of the major retinol carriers found in the blood of mammals. Humans RBP4 is a monomeric 21 kDa .beta.-sheet-rich protein that contains three disulfide bonds and belongs to the lipocalin protein family. sRBP4 is synthesized and sequestered in hepatocytes until retinol binding triggers its secretion . In plasma, sRBP4 typically forms a 1:1 complex with the 55 kDa tetrameric protein transthyretin -TTR) which prevents RBP from being removed from the plasma by glomerular filtration. Studies have shown that sRBP4 is an adipocyte-derived signal that may contribute to the pathogenesis of type 2 diabetes. Elevation of sRBP4 causes systemic insulin resistance whereas reduction of serum concentrations improves insulin action.
- 序列
- 來源宿主
- 溶解建議
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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