- 中文名稱
PCSK9 WB即用型對照 (1 ea)
- 英文名字
- PCSK9 Western Ready Control (1 ea)
- 供應商
- Cayman
- 產品貨號
- 10009567-1
- 產品報價
- ￥714/1 ea
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Proprotein convertase subtilisin kexin 9 -PCSK9) is a member of the subtilisin serine protease family with an important role in low density lipoprotein -LDL) metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in low density lipoprotein cholesterol levels. PCSK9 overexpression in wild-type mice doubles the plasma total cholesterol, possibly through acceleration of the degradation of the LDL receptor. PCSK9 mRNA is detected in various tissues such as liver, kidney, lung, spleen, jejunum, ileum, colon, and muscles with the highest expression in the liver. Human PCSK9 precursor is 692 amino acid in length with an estimated molecular weight of 74 kDa. This proprotein is self-cleaved to form a mature protein at around 63 kDa in the golgi.
- 序列
- 來源宿主
- 溶解建議
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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