- 中文名稱
9-Z),11-E),13-E)-Octadecatrienoic Acid methyl ester (50 mg)
- 英文名字
- Methyl
- 供應商
- Cayman
- 產品貨號
- 10008333-50
- 產品報價
- ￥7840/50 mg
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- 9Z,11E,13E-octadecatrienoic acid -.alpha.-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. .alpha.-ESA is metabolized and converted to conjugated linoleic acid -9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, .alpha.-ESA induced apoptosis through up-regulation of GADD45, p53, and PPAR.gamma.. In DLD-1 cells supplemented with .alpha.-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 uM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 uM for different isoforms of the enzymes. .alpha.-ESA methyl ester is a neutral, more lipid soluble form of the free acid.
- 產品描述
- .alpha.-ESA methyl ester is a neutral, more lipid soluble form of the free acid.
- 產品形式
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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