- 中文名稱
Gestrinone (5 g)
- 英文名字
- Gestrinone, 13-ethyl-17.alpha.-hydroxy-18,19-dinorpregna-4,9,11-trien-2-yn-3-one
- 供應商
- Cayman
- 產品貨號
- 10006488-5
- 產品報價
- ￥47530/5 g
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis. It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone -LH) and follicle-stimulating hormone -FSH), thus reducing estrogen synthesis. It also binds to androgen -AR), progesterone -PR), and estrogen -ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin. Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively. These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.
- 產品描述
- Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis.{12994} It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone -LH) and follicle-stimulating hormone -FSH), thus reducing estrogen synthesis.{12994} It also binds to androgen -AR), progesterone -PR), and estrogen -ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin.{13002} Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively.{12992} These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.{12992}
- 產品形式
- 保存建議
- -20
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
