Montana Molecular-PIP2檢測試劑盒：低毒性，實時動態讀數

Montana Molecular-PIP2檢測試劑盒的性能：

基因編碼，低毒性

PIP2傳感器和對照組包含在BSL-1級的BacMam載體中，可在多種細胞中有效表達

單通道讀數可以與額外的GPCR檢測結合使用

實時動態讀數

多重檢測試驗：

結合紅色和綠色傳感器，可以同時測量多個GPCR信號通路

艾美捷 Montana Molecular-PIP2檢測試劑盒簡單的操作流程：

無需細胞裂解

單通道讀數

BSL-1級載體

控制表達水平

Montana Molecular-PIP2檢測試劑盒文獻參考：

L. Brueggemann, et al. Structural Determinants of Kv7.5 Potassium Channels that Confer Changes in Phosphatidylinositol 4,5-Biphosphate (PIP2) Affinity and Signaling Sensitivity in Smooth Muscle Cells. Molecular Pharmacology. March 2020.

L.Liu, et al. Gαq sensitizes TRPM8 to inhibition by PI(4,5)P2 depletion upon receptor activation. J.Neurosci. May 2019.

Alexey N. Pronin, Qiang Wang and Vladlen Z. Slepak Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor Molecular Pharmacology Nov. 2018

Y. Ding, et al. Ratiometric biosensors based on dimerization dependent fluorescent protein exchange. Nature Methods, 2015.

P. Tewson, et al. A multiplexed fluorescent assay for independent second-messenger systems: decoding GPCR activation in living cells. J. Biomolecular Screening 18, 2013.

Montana Molecular產品主要包括GPCR檢測、細胞應激和毒性相關檢測工具，為客戶提供了長時間內觀察候選藥物對細胞過程影響的能力。艾美捷科技是Montana Molecular的中國代理商，為科研工作者提供優質的產品與服務。