香葉基二磷酸（GPP），助力天然產物研究

香葉基焦磷酸（GPP）是異戊二烯生物合成途徑中的一個中間體。異戊二烯類化合物是一類多樣的天然產物，是所有細胞中的必需成分。異戊二烯類化合物是由簡單的前體物質異戊二烯焦磷酸（IPP）和二甲基烯丙基焦磷酸（DMAPP）生物合成的。真核生物、真菌和一些革蘭氏陽性菌通過甲羥戊酸（MVA）途徑產生IPP，而革蘭氏陰性菌和一些革蘭氏陽性菌則利用非甲羥戊酸途徑或2-C-甲基-D-赤蘚糖醇-4-磷酸（MEP）途徑。GPP是由二甲基烯丙基焦磷酸（DMAPP）和異戊二烯焦磷酸（IPP）在香葉基焦磷酸合酶的催化下縮合形成的。

艾美捷香葉基二磷酸（GPP）：

貨號：I-0100

分類：生物化學試劑

篩選：異戊二烯類、異戊二烯焦磷酸

CAS號：104715-14-2

分子式：C10H29N3O7P2

分子量（g/mol）：365.3

純度：95%

保存條件：-20°C或更低

運輸溫度：冰膠

香葉基二磷酸（GPP）文獻參考：

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4. Falara, V., Akhtar, T. A., Nguyen, T. T. H., Spyropoulou, E. A., Bleeker, P. M., Schauvinhold, I., … Pichersky, E. (2011). “The tomato terpene synthase gene family.” Plant Physiology, 157(2), 770-789. DOI:10.1104/pp.111.179648

5. Blank, P. N., et al. (2017). “Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.” Biochemistry 56(43): 5798-5811.

6. Rea, K. A., et al. (2019). “Biosynthesis of cannflavins A and B from Cannabis sativa L.” Phytochemistry 164: 162-171.