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特色產品2A3單克隆抗體與三硝基苯酚反應。由于哺乳動物不表達三硝基苯酚,這種抗體非常適合在大多數體內和體外應用中用作大鼠IgG2a抗體的同種型匹配對照。

艾美捷InVivoMAb大鼠IgG2a同種型對照,抗三硝基苯酚:
貨號:BXC-BE0089
亞型:大鼠IgG2a,κ
由LAL凝膠凝固測定法確定
推薦稀釋液:InVivoPure pH 6.5稀釋液
偶聯:未偶聯。提供抗體偶聯服務。
配方:PBS,pH 6.5
不含穩定劑或防腐劑
內毒素:<2EU/毫克(<0.002EU/微克)
由LAL凝膠凝固測定法確定
純度:>95%
由SDS-PAGE確定
無菌性:0.2微米過濾
在無動物設施中從細胞培養上清液中純化
純化:蛋白質G
分子量:150 kDa
儲存:抗體溶液應以原始濃度在4°C下儲存。不要冷凍。
InVivoMAb大鼠IgG2a同種型對照文獻參考:
Bauche, D., et al. (2018). "LAG3(+) Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1(+) Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis" Immunity 49(2): 342-352 e345.
Ngiow, S. F., et al. (2015). "A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1" Cancer Res 75(18): 3800-3811.
Dai, M., et al. (2015). "Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies" Clin Cancer Res 21(5): 1127-1138.
Kurtulus, S., et al. (2015). "TIGIT predominantly regulates the immune response via regulatory T cells" J Clin Invest. doi : 10.1172/JCI81187.
Ellis, G. T., et al. (2015). "TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection" EMBO Rep 16(9): 1203-1218.
Walsh, K. B., et al. (2014). "Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy" J Virol 88(11): 6281-6293.

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